Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEF2D All Species: 21.82
Human Site: S437 Identified Species: 40
UniProt: Q14814 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14814 NP_005911.1 521 55938 S437 V T T H P H I S I K S E P V S
Chimpanzee Pan troglodytes XP_001165500 521 55889 S437 V T T H P H I S I K S E P V S
Rhesus Macaque Macaca mulatta XP_001103222 500 53974 Q418 P S G F Q Q Q Q Q Q Q P P P P
Dog Lupus familis XP_547534 525 56508 P419 R E R S P A P P P P A V F P A
Cat Felis silvestris
Mouse Mus musculus Q63943 514 54974 S430 V T T H P H I S I K S E P V S
Rat Rattus norvegicus O89038 507 54350 S423 V T T H P H I S I K S E P V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507540 505 54598 Q421 P S G F P Q Q Q Q Q Q Q Q Q Q
Chicken Gallus gallus Q9W6U8 499 53650 Q422 S S G F P Q Q Q P P Q Q P Q P
Frog Xenopus laevis Q03413 498 54053 S411 N T N P I N I S I K R E P A S
Zebra Danio Brachydanio rerio NP_571392 529 57466 S422 V N T N P S I S I K S E P V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40791 539 57097 E434 G G S N G N V E Q A T N L S V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38847 268 30310 N191 C F A I D P K N A L I N H D S
Baker's Yeast Sacchar. cerevisiae Q12224 676 73465 S531 I S M F P D W S M G P N S A K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 53.7 72.5 N.A. 96.1 94.4 N.A. 54.1 54.7 73.6 70.1 N.A. 28 N.A. N.A. N.A.
Protein Similarity: 100 99.8 63.9 75.8 N.A. 97.1 95.5 N.A. 64.8 64.3 82.5 78.2 N.A. 39.5 N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 6.6 N.A. 100 100 N.A. 6.6 13.3 53.3 80 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 20 20 N.A. 100 100 N.A. 26.6 26.6 60 86.6 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.2 22.1 N.A.
Protein Similarity: N.A. N.A. N.A. 34.9 38.4 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 8 0 0 8 8 8 0 0 16 8 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 8 0 0 0 0 0 0 0 8 0 % D
% Glu: 0 8 0 0 0 0 0 8 0 0 0 47 0 0 0 % E
% Phe: 0 8 0 31 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 8 8 24 0 8 0 0 0 0 8 0 0 0 0 0 % G
% His: 0 0 0 31 0 31 0 0 0 0 0 0 8 0 0 % H
% Ile: 8 0 0 8 8 0 47 0 47 0 8 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 47 0 0 0 0 8 % K
% Leu: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % L
% Met: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 8 8 8 16 0 16 0 8 0 0 0 24 0 0 0 % N
% Pro: 16 0 0 8 70 8 8 8 16 16 8 8 62 16 16 % P
% Gln: 0 0 0 0 8 24 24 24 24 16 24 16 8 16 8 % Q
% Arg: 8 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 8 31 8 8 0 8 0 54 0 0 39 0 8 8 54 % S
% Thr: 0 39 39 0 0 0 0 0 0 0 8 0 0 0 0 % T
% Val: 39 0 0 0 0 0 8 0 0 0 0 8 0 39 8 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _